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ALG1

Description ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Cytoplasmic Side Of Endoplasmic Reticulum Membrane
Molecular Function
  • Mannosyltransferase Activity
  • Chitobiosyldiphosphodolichol Beta-mannosyltransferase Activity
  • Transferase Activity
  • Glycosyltransferase Activity
Biological Process
  • Protein Glycosylation
  • Protein N-linked Glycosylation
  • Dolichol-linked Oligosaccharide Biosynthetic Process
Pathways
  • Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
  • Defective ALG1 causes CDG-1k
Drugs
Diseases
  • Congenital disorders of glycosylation (CDG) type I
GWAS
  • Metabolite levels ( 23823483)
  • Phospholipid levels (plasma) ( 22359512)
Interacting Genes 1 interacting genes: UBC
Entrez ID 56052
HPRD ID 10437
Ensembl ID ENSG00000033011
Uniprot IDs A0A804HJL6 Q9BT22
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Protein Tag Activity
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© Madhavi K. Ganapathiraju 2012-2025