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GNG12
Gene Name
guanine nucleotide binding protein (G protein), gamma 12
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Heterotrimeric G-protein Complex
Actin Filament
Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Signal Transducer Activity
PDZ Domain Binding
Phosphate Ion Binding
Biological Process
Energy Reserve Metabolic Process
Signal Transduction
G-protein Coupled Receptor Signaling Pathway
Synaptic Transmission
Cerebral Cortex Development
Response To Lipopolysaccharide
Small Molecule Metabolic Process
Cellular Response To Glucagon Stimulus
Pathways
Signaling by GPCR
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 1
Integration of energy metabolism
G alpha (s) signalling events
Activation of GABAB receptors
Glucagon-type ligand receptors
G beta:gamma signalling through PLC beta
Signaling by Wnt
Metabolic disorders of biological oxidation enzymes
G protein gated Potassium channels
Gastrin-CREB signalling pathway via PKC and MAPK
Thromboxane signalling through TP receptor
G alpha (z) signalling events
G alpha (i) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ADP signalling through P2Y purinoceptor 12
Glucagon signaling in metabolic regulation
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Inwardly rectifying K+ channels
G-protein beta:gamma signalling
Opioid Signalling
Activation of Kainate Receptors upon glutamate binding
Aquaporin-mediated transport
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (q) signalling events
GPCR downstream signaling
Platelet homeostasis
Platelet activation, signaling and aggregation
Transmission across Chemical Synapses
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signal amplification
Potassium Channels
G beta:gamma signalling through PI3Kgamma
G alpha (12/13) signalling events
Class B/2 (Secretin family receptors)
Prostacyclin signalling through prostacyclin receptor
GABA B receptor activation
GABA receptor activation
Activation of G protein gated Potassium channels
Vasopressin regulates renal water homeostasis via Aquaporins
Regulation of insulin secretion
GPCR ligand binding
beta-catenin independent WNT signaling
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Ca2+ pathway
G-protein activation
Drugs
Diseases
GWAS
Protein-protein Interactions
6 interactors:
CAPN1
FHL2
GNB1
GNB2
GNB3
GNB4
Entrez ID
55970
HPRD ID
13592
Ensembl ID
ENSG00000172380
Uniprot IDs
Q9UBI6
PDB IDs
Enriched GO Terms of Interacting Partners
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Cellular Response To Glucagon Stimulus
Response To Glucagon
Energy Reserve Metabolic Process
Energy Derivation By Oxidation Of Organic Compounds
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Response To Hormone
Generation Of Precursor Metabolites And Energy
Response To Peptide Hormone
Cellular Response To Organonitrogen Compound
Response To Peptide
Cellular Response To Hormone Stimulus
Response To Organonitrogen Compound
Small Molecule Metabolic Process
Response To Organic Substance
Oxidation-reduction Process
Synaptic Transmission
Cellular Response To Organic Substance
Atrial Cardiac Muscle Cell Development
Cell-cell Signaling
Cardiac Muscle Cell Apoptotic Process
Muscle Cell Apoptotic Process
G-protein Coupled Receptor Signaling Pathway
Signal Transduction
Receptor Catabolic Process
Cellular Response To Prostaglandin E Stimulus
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Signaling
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Cell Communication
Heart Trabecula Formation
Ventricular Cardiac Muscle Cell Development
Response To Prostaglandin E
Cellular Response To Prostaglandin Stimulus
Cellular Metabolic Process
Regulation Of Rhodopsin Mediated Signaling Pathway
Cellular Response To Catecholamine Stimulus
Heart Trabecula Morphogenesis
Ventricular Cardiac Muscle Cell Differentiation
Cellular Response To Stimulus
Rhodopsin Mediated Signaling Pathway
Dopamine Receptor Signaling Pathway
Substantia Nigra Development
Androgen Receptor Signaling Pathway
Cellular Response To Fatty Acid
Trabecula Morphogenesis
Neural Nucleus Development
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Tagcloud
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prkca
reaching
u133a