AJAP1

Description		adherens junctions associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Cytoplasmic Side Of Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cell-cell Contact Zone Anchoring Junction
	Molecular Function	Protein Binding Beta-catenin Binding Protein Domain Specific Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Cell Adhesion Regulation Of Polarized Epithelial Cell Differentiation Negative Regulation Of Wound Healing
Pathways
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 26394188) Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Bitter beverage consumption ( 31046077) Carotid plaque burden ( 28282560) Chronotype ( 30696823) Dental caries ( 23064961) Diffusing capacity of carbon monoxide ( 30694715) Maximum retinal venular tortuosity ( 31597446) Migraine - clinic-based ( 23793025) Nickel levels ( 26025379) QT interval ( 29213071) Response to haloperidol in schizophrenia ( 29503163) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189) Smooth-surface caries ( 24556642) Systemic juvenile idiopathic arthritis ( 27927641) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Verbal declarative memory ( 25648963)
Interacting Genes		1 interacting genes: CTNNB1
Entrez ID		55966
HPRD ID		15339
Ensembl ID		ENSG00000196581
Uniprot IDs		Q9UKB5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Mesenchymal Stem Cell Differentiation Oviduct Development Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Beta-catenin-ICAT Complex Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Acinar Cell Differentiation Positive Regulation Of Proteoglycan Biosynthetic Process Fungiform Papilla Formation Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Beta-catenin-TCF7L2 Complex Glial Cell Fate Determination Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Metanephros Morphogenesis Trachea Morphogenesis Regulation Of Mitotic Cell Cycle, Embryonic Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Regulation Of Centriole-centriole Cohesion Renal Outer Medulla Development Renal Vesicle Formation Embryonic Skeletal Limb Joint Morphogenesis Glial Cell-neuron Signaling Lung Induction Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Catenin-TCF7L2 Complex Regulation Of Timing Of Anagen Cellular Response To Indole-3-methanol Mesenchymal Cell Proliferation Involved In Lung Development Central Nervous System Vasculogenesis Cranial Ganglion Development Regulation Of Centromeric Sister Chromatid Cohesion Hair Follicle Placode Formation Dorsal Root Ganglion Development Establishment Of Blood-retinal Barrier Response To Indole-3-methanol Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Blood Vessel Branching Endodermal Cell Fate Commitment Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Limb Joint Morphogenesis Detection Of Muscle Stretch Regulation Of Secondary Heart Field Cardioblast Proliferation Positive Regulation Of Odontoblast Differentiation
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