ECHDC1

Name	ethylmalonyl-CoA decarboxylase 1
Structure	No pdb structure
Interactors	3 interactors: APP GORASP2 VKORC1
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Catalytic Activity Methyl/ethyl Malonyl-CoA Decarboxylase Activity Protein Binding Lyase Activity Carboxy-lyase Activity
	Biological Process	Fatty Acid Beta-oxidation
GWAS	Breast cancer ( 18326623 ) Diffusing capacity of carbon monoxide ( 30694715 ) Hip index ( 34021172 ) Left-handedness ( 32989287 ) Mean spheric corpuscular volume ( 32888494 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172 ) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Entrez ID	55862
HPRD ID	13260
Ensembl ID	ENSG00000093144
Uniprot IDs	Q9NTX5
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Endoplasmic Reticulum Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Endoplasmic Reticulum Lumen Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Quinone Binding Antifungal Humoral Response Nuclear Envelope Lumen Acetylcholine Receptor Binding Neuron Projection Maintenance RAGE Receptor Binding Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation