FGD6

Gene Name		FYVE, RhoGEF and PH domain containing 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Golgi Apparatus Cytoskeleton Lamellipodium
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Small GTPase Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Rho GTPase Activity Regulation Of Cdc42 GTPase Activity Positive Regulation Of GTPase Activity Filopodium Assembly
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065)
Protein-protein Interactions		2 interactors: ACVR1 YWHAG
Entrez ID		55785
HPRD ID		16892
Ensembl ID		ENSG00000180263
Uniprot IDs		Q6ZV73
PDB IDs
Enriched GO Terms of Interacting Partners?		Endocardial Cushion Cell Fate Commitment Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitral Valve Morphogenesis Cardiac Muscle Cell Fate Commitment Mitral Valve Development Cellular Response To Hormone Stimulus Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Activin Receptor Signaling Pathway Atrial Septum Primum Morphogenesis Endocardial Cell Differentiation Mitotic Cell Cycle Process Septum Primum Development Mitotic Cell Cycle Pathway-restricted SMAD Protein Phosphorylation Muscle Cell Fate Commitment Pharyngeal System Development Endocardium Development Atrial Septum Morphogenesis Response To Hormone Atrioventricular Valve Morphogenesis Atrial Septum Development Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Atrioventricular Valve Development Epithelial Cell Fate Commitment Cell Cycle Process Regulation Of Protein Phosphorylation Activin Receptor Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cardiac Atrium Morphogenesis Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Heart Valve Morphogenesis Positive Regulation Of Signal Transduction Heart Valve Development Regulation Of Phosphorylation Endocardial Cushion Development Cell Cycle Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Patterning Of Blood Vessels Regulation Of Apoptotic Process Neural Crest Cell Migration Peptidyl-threonine Phosphorylation Regulation Of Phosphorus Metabolic Process Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Regulation Of Cell Death Smooth Muscle Cell Differentiation
Tagcloud ?		actin anxa2 automated beyond cofilin coincided dephosphorylation depletion dnajc6 egfr endocytosis endosomes gdi2 hax1 hbl100 inactive knockdown mb mda mediator mediators necap2 re rnas s3a s3e semi severing tnbc