STAP2

Description		signal transducing adaptor family member 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Signaling Adaptor Activity
	Biological Process
Pathways		PTK6 Activates STAT3 Cytoprotection by HMOX1
Drugs
Diseases
GWAS		Tea consumption ( 31046077)
Interacting Genes		19 interacting genes: BLK BMP4 CBL CFTR CHUK CSF1R EGFR IKBKB JAK2 KEAP1 MLH1 MYD88 PTK6 SRC STAT3 STAT5A STAT5B TXK YES1
Entrez ID		55620
HPRD ID		07430
Ensembl ID		ENSG00000178078
Uniprot IDs		Q9UGK3
PDB IDs		2EL8
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Signaling Pathway Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Cytokine-mediated Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Immune Response Regulation Of Immune System Process Protein Kinase Activity Positive Regulation Of Immune System Process Response To Cytokine Response To Peptide Positive Regulation Of Cell Communication Positive Regulation Of Signaling Kinase Activity Immune System Process Regulation Of Multicellular Organismal Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Immune Response Positive Regulation Of Macromolecule Metabolic Process Growth Hormone Receptor Signaling Pathway Via JAK-STAT Peptidyl-tyrosine Phosphorylation ATP Binding Response To Lipid Phosphorylation Positive Regulation Of Metabolic Process Immune Effector Process Regulation Of Defense Response Cellular Developmental Process Signal Transduction Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Signal Transduction Growth Hormone Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Defense Response Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Innate Immune Response Positive Regulation Of Biosynthetic Process Nucleotide Binding Positive Regulation Of Cytokine Production Regulation Of Lymphocyte Activation Positive Regulation Of Lymphocyte Activation Protein Phosphorylation Immune Response-activating Signaling Pathway Regulation Of Cytokine Production Cell Differentiation Positive Regulation Of Intracellular Signal Transduction
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