MTMR8

Description		myotubularin related protein 8
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Phosphatidylinositol-3-phosphate Phosphatase Activity Protein Binding Hydrolase Activity Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Phosphatidylinositol-3,5-bisphosphate Phosphatase Activity
	Biological Process	Lipid Metabolic Process Negative Regulation Of Autophagy Regulation Of Macroautophagy Phosphatidylinositol Metabolic Process Phosphatidylinositol Dephosphorylation
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: AATK ERBB3 MTMR9
Entrez ID		55613
HPRD ID		06664
Ensembl ID		ENSG00000102043
Uniprot IDs		Q96EF0
PDB IDs		4Y7I
Enriched GO Terms of Interacting Partners?		Neuron Apoptotic Process Protein Tyrosine Kinase Activity Positive Regulation Of Cardiac Muscle Tissue Development ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Neuregulin Receptor Activity Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Phosphatase Activity Regulation Of Phosphatidylinositol Dephosphorylation Positive Regulation Of Dephosphorylation Schwann Cell Differentiation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Phosphatase Activity Negative Regulation Of Motor Neuron Apoptotic Process Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process Protein Kinase Activity Endocardial Cushion Development Protein Tyrosine Kinase Activator Activity Positive Regulation Of Striated Muscle Tissue Development Kinase Activity Schwann Cell Development ERBB2 Signaling Pathway Positive Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Dephosphorylation Phosphatidylinositol Dephosphorylation Peripheral Nervous System Development Perinuclear Region Of Cytoplasm Enzyme Regulator Activity Cranial Nerve Development Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Phospholipid Dephosphorylation Regulation Of Phospholipid Metabolic Process Regulation Of Striated Muscle Tissue Development Growth Factor Binding Apoptotic Process Regulation Of Muscle Organ Development Cell Death Nerve Development Programmed Cell Death Positive Regulation Of Calcium-mediated Signaling Mesenchyme Development Glial Cell Development Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Lateral Plasma Membrane
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