BMP2K

Description		BMP2 inducible kinase
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Phosphatase Regulator Activity AP-2 Adaptor Complex Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Bone Mineralization Positive Regulation Of Notch Signaling Pathway Regulation Of Clathrin-dependent Endocytosis
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Aspartate aminotransferase levels ( 29403010) Common carotid intima-media thickness in HIV infection ( 29206233) Daytime nap ( 33568662) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494 29403010) Mean spheric corpuscular volume ( 32888494) Non-albumin protein levels ( 29403010) Platelet distribution width ( 32888494) Red cell distribution width ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum albumin levels ( 29403010) Serum total protein levels ( 29403010)
Interacting Genes		1 interacting genes: MBP
Entrez ID		55589
HPRD ID		09828
Ensembl ID		ENSG00000138756
Uniprot IDs		Q9NSY1
PDB IDs		4W9W 4W9X 5I3O 5I3R 5IKW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metalloendopeptidase Activity Regulation Of Metallopeptidase Activity Internode Region Of Axon Compact Myelin Negative Regulation Of Heterotypic Cell-cell Adhesion Structural Constituent Of Myelin Sheath Positive Regulation Of Peptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Endopeptidase Activity Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Myelin Sheath Maintenance Of Blood-brain Barrier Substantia Nigra Development Neural Nucleus Development Positive Regulation Of Chemokine Production Cell Periphery Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Myelination Response To Toxic Substance Axon Ensheathment Protease Binding Positive Regulation Of Hydrolase Activity Sensory Perception Of Mechanical Stimulus Sensory Perception Of Sound Central Nervous System Development Regulation Of Interleukin-6 Production Anatomical Structure Homeostasis Tissue Homeostasis Calmodulin Binding Positive Regulation Of Proteolysis Negative Regulation Of Cell-cell Adhesion MAPK Cascade Positive Regulation Of Catalytic Activity Negative Regulation Of Cell Adhesion Chemical Synaptic Transmission Lipid Binding Trans-synaptic Signaling Synaptic Signaling Neuronal Cell Body
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