ASIC4

Description		acid sensing ion channel subunit family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Sodium Channel Activity Protein Binding Ligand-gated Sodium Channel Activity
	Biological Process	Behavioral Fear Response Monoatomic Ion Transport Sodium Ion Transport Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS		Cerebrospinal fluid sTREM-2 levels ( 31708768) Lung function (FVC) ( 30804560)
Novel Interacting Genes		1 novel interacting genes: TRIM32
Interacting Genes		3 interacting genes: CFTR OTX2 ZDHHC17
Entrez ID		55515
HPRD ID		16231
Ensembl ID		ENSG00000072182
Uniprot IDs		A0A8I5KPF5 Q96FT7
PDB IDs
Enriched GO Terms of Interacting Partners?		Golgi-associated Vesicle Membrane Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Interleukin-17-mediated Signaling Pathway Actin Ubiquitination Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Perforant Pathway To Dendrate Granule Cell Synapse Positive Regulation Of Anion Channel Activity Protein Localization To Phagocytic Vesicle Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Positive Regulation Of Monoatomic Anion Transport Striated Muscle Myosin Thick Filament Positive Regulation Of Enamel Mineralization Actin Modification Cell Projection Organization Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Cell Communication Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Signaling Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Gastrulation Free Ubiquitin Chain Polymerization Cytosolic Ciliogenesis Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Developmental Process Eukaryotic Initiation Factor 4E Binding Regulation Of Multicellular Organismal Development Amelogenesis Regulation Of Canonical NF-kappaB Signal Transduction ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Cellular Response To Growth Factor Stimulus Tat Protein Binding Primitive Streak Formation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Regulation Of Gastrulation Cellular Response To Forskolin Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Cell Communication Chloride Transmembrane Transporter Activity
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