TNFRSF19

Description		TNF receptor superfamily member 19
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Tumor Necrosis Factor Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Hair Follicle Development Apoptotic Process JNK Cascade Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of JNK Cascade
Pathways
Drugs
Diseases
GWAS		Blood pressure (smoking interaction) ( 25189868) Blood protein levels ( 30072576) Diabetic kidney disease ( 26305897) Heel bone mineral density ( 30598549) Hypothyroidism ( 22493691) Nasopharyngeal carcinoma ( 20512145 26545403) Visceral adipose tissue adjusted for BMI ( 22589738)
Novel Interacting Genes		1 novel interacting genes: ARID1B
Interacting Genes		9 interacting genes: GIMAP5 MTURN SGTA SGTB TRAF1 TRAF2 TRAF3 TRAF5 TRAF6
Entrez ID		55504
HPRD ID		05838
Ensembl ID		ENSG00000127863
Uniprot IDs		Q9NS68
PDB IDs
Enriched GO Terms of Interacting Partners?		Tumor Necrosis Factor Receptor Binding Thioesterase Binding CD40 Receptor Complex Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Signaling Adaptor Activity CD40 Signaling Pathway Interleukin-17-mediated Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity TRC Complex Cytoplasmic Side Of Plasma Membrane Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Canonical NF-kappaB Signal Transduction Cytokine-mediated Signaling Pathway Identical Protein Binding Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRIF-dependent Toll-like Receptor Signaling Pathway Ubiquitin Protein Ligase Binding Positive Regulation Of JUN Kinase Activity MyD88-independent Toll-like Receptor Signaling Pathway Ubiquitin Protein Ligase Activity Regulation Of JNK Cascade Protein Targeting To ER Positive Regulation Of T Cell Cytokine Production Non-canonical NF-kappaB Signal Transduction Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of MAP Kinase Activity Positive Regulation Of Interleukin-2 Production Signal Transduction Involved In Regulation Of Gene Expression Regulation Of T Cell Cytokine Production Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Canonical NF-kappaB Signal Transduction Toll-like Receptor 4 Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Positive Regulation Of Gene Expression Regulation Of Intracellular Signal Transduction Ubiquitin-protein Transferase Activity Toll-like Receptor Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Endosome Membrane MRNA Transcription TORC2 Complex Disassembly Regulation Of Interleukin-2 Production Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of MAP Kinase Activity MRNA Stabilization Regulation Of Apoptotic Process
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