MEG3

Description		maternally expressed 3
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex
	Molecular Function	DsDNA-RNA Triple Helix-forming Chromatin Adaptor Activity
	Biological Process	Chromatin Organization Negative Regulation Of Cell Growth MiRNA-mediated Post-transcriptional Gene Silencing
Pathways
Drugs
Diseases
GWAS		Optic nerve measurement (disc area) ( 20395239) Type 1 diabetes ( 19966805) Type 2 diabetes ( 32499647)
Interacting Genes		4 interacting genes: CTNNB1 GSK3B RSPH1 STAT3
Entrez ID		55384
HPRD ID
Ensembl ID		ENSG00000214548
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		Beta-catenin Destruction Complex Wnt Signalosome RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Stem Cell Differentiation Mesenchymal Stem Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Determination Of Dorsal Identity Regulation Of Osteoblast Differentiation Negative Regulation Of Mitotic Cell Cycle, Embryonic Regulation Of Cell Development Beta-catenin-ICAT Complex Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Positive Regulation Of Neuron Apoptotic Process Enzyme-linked Receptor Protein Signaling Pathway Glial Cell Fate Determination Canonical Wnt Signaling Pathway Intracellular Signaling Cassette Negative Regulation Of Intracellular Signal Transduction Nervous System Development Maintenance Of Cell Number Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Response To Estradiol Schaffer Collateral - CA1 Synapse Protein Kinase Binding Renal Outer Medulla Development Regulation Of Anatomical Structure Morphogenesis Renal Vesicle Formation Negative Regulation Of Cell Differentiation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Glial Cell Differentiation Protein Phosphatase Binding Stem Cell Population Maintenance Response To Lipid Mesenchymal Cell Differentiation Glutamatergic Synapse Superior Temporal Gyrus Development Regulation Of Membrane Permeability Negative Regulation Of Type B Pancreatic Cell Development Regulation Of Stem Cell Differentiation Mitochondrial Membrane Organization Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Microtubule Anchoring At Centrosome
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