TMCO6

Description		transmembrane and coiled-coil domains 6
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Schizophrenia ( 28991256 29483656) Serum immune biomarker levels ( 32066700)
Interacting Genes		1 interacting genes: UBQLN1
Entrez ID		55374
HPRD ID		15177
Ensembl ID		ENSG00000113119
Uniprot IDs		A8K0D0 Q96DC7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Aggrephagy Positive Regulation Of ERAD Pathway Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transporter Activity Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Aggresome Negative Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Calcium Ion Transport Autophagosome Maturation Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Proteasome Complex Autophagosome Kinase Binding Regulation Of Transmembrane Transporter Activity Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Cation Transmembrane Transport Autophagosome Organization Autophagosome Assembly Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway ERAD Pathway Negative Regulation Of Monoatomic Ion Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transporter Activity Positive Regulation Of Protein Ubiquitination Negative Regulation Of Transmembrane Transport Positive Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Decreased Oxygen Levels Positive Regulation Of Post-translational Protein Modification Cellular Response To Hypoxia Regulation Of Calcium Ion Transmembrane Transport Protein-containing Complex Disassembly Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To Oxygen Levels Macroautophagy Vacuole Organization Regulation Of Protein Ubiquitination Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Macroautophagy Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Calcium Ion Transport Response To Endoplasmic Reticulum Stress Regulation Of Post-translational Protein Modification Regulation Of Monoatomic Cation Transmembrane Transport
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