TMEM63B

Description		transmembrane protein 63B
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Actin Cytoskeleton Membrane Early Endosome Membrane Alveolar Lamellar Body Membrane
	Molecular Function	Calcium-activated Cation Channel Activity Mechanosensitive Monoatomic Ion Channel Activity Phospholipid Scramblase Activity Phosphatidylcholine Transfer Activity Mechanosensitive Monoatomic Cation Channel Activity Sphingomyelin Transfer Activity Osmolarity-sensing Monoatomic Cation Channel Activity
	Biological Process	Monoatomic Ion Transport Exocytosis Sensory Perception Of Sound Phospholipid Transport Plasma Membrane Phospholipid Scrambling Monoatomic Ion Transmembrane Transport Intestinal Stem Cell Homeostasis Drinking Behavior Monoatomic Cation Transmembrane Transport Intermembrane Lipid Transfer Surfactant Secretion
Pathways
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		1 interacting genes: MAPK14
Entrez ID		55362
HPRD ID		16656
Ensembl ID		ENSG00000137216
Uniprot IDs		Q5T3F8
PDB IDs		8EHX 8XW4
Enriched GO Terms of Interacting Partners?		Cell Aggregation Positive Regulation Of Myotube Differentiation Positive Regulation Of Heart Growth Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Hippo Signaling 3'-UTR-mediated MRNA Stabilization Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Proliferation Regulation Of Brown Fat Cell Differentiation Cellular Response To Lipoteichoic Acid P38MAPK Cascade Hexose Transmembrane Transport Regulation Of Hippo Signaling Cellular Response To UV-B Response To UV-B Regulation Of Myotube Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway D-glucose Import Positive Regulation Of D-glucose Import Cellular Response To Vascular Endothelial Growth Factor Stimulus D-glucose Transmembrane Transport Carbohydrate Transmembrane Transport Positive Regulation Of D-glucose Transmembrane Transport MAP Kinase Activity Osteoclast Differentiation Positive Regulation Of Myoblast Fusion Positive Regulation Of Organ Growth Cartilage Condensation Mitogen-activated Protein Kinase P38 Binding Pyroptotic Inflammatory Response MAP Kinase Kinase Activity Positive Regulation Of Cyclase Activity Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Positive Regulation Of Striated Muscle Cell Differentiation Stress-activated MAPK Cascade Placenta Development Negative Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Synaptic Membrane Adhesion Regulation Of Myoblast Fusion Positive Regulation Of Protein Import Into Nucleus Carbohydrate Transport Positive Regulation Of Interleukin-12 Production NFAT Protein Binding Stress-induced Premature Senescence Canonical Inflammasome Complex Assembly Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Myoblast Differentiation Response To Muramyl Dipeptide
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