FBXL8

Description		F-box and leucine rich repeat protein 8
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Protein Binding
	Biological Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: ALAS1 ORC4 PICK1 SKP1
Entrez ID		55336
HPRD ID		16430
Ensembl ID		ENSG00000135722
Uniprot IDs		Q96CD0
PDB IDs
Enriched GO Terms of Interacting Partners?		Heme O Biosynthetic Process Hemoglobin Metabolic Process Response To Herbicide Response To Cobalt Ion 5-aminolevulinate Synthase Activity Response To Nickel Cation Response To Bile Acid Response To Platinum Ion Response To Oxygen Levels Heme A Biosynthetic Process Protoporphyrinogen IX Biosynthetic Process Protoporphyrinogen IX Metabolic Process Response To Decreased Oxygen Levels Hemoglobin Biosynthetic Process Heme B Biosynthetic Process Nuclear Origin Of Replication Recognition Complex Meiotic Cytokinesis Origin Recognition Complex Polar Body Extrusion After Meiotic Divisions Protein Domain Specific Binding F-box Domain Binding Cul7-RING Ubiquitin Ligase Complex Ubiquitin Ligase Complex Scaffold Activity Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Curvature Sensor Activity Negative Regulation Of Actin Nucleation Neuronal Ion Channel Clustering Dendritic Spine Maintenance Ubiquitin Ligase Activator Activity Arp2/3 Complex Binding DNA Replication Origin Binding Long-term Synaptic Depression Response To Nutrient Levels Response To Gonadotropin Tetrapyrrole Biosynthetic Process Macromolecule Metabolic Process Heme Biosynthetic Process Porphyrin-containing Compound Biosynthetic Process DNA Replication Initiation Maintenance Of Protein Location In Nucleus PcG Protein Complex Cullin Family Protein Binding Molecular Function Activator Activity Positive Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Receptor Internalization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Monoamine Transport Erythrocyte Development Dendritic Spine Organization Heme Metabolic Process
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