ACER3

Gene Name		alkaline ceramidase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Phytoceramidase Activity
	Biological Process	Sphingolipid Metabolic Process Ceramide Metabolic Process Positive Regulation Of Cell Proliferation Sphingolipid Biosynthetic Process Small Molecule Metabolic Process Sphingosine Biosynthetic Process Phytosphingosine Biosynthetic Process
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: MLH1
Entrez ID		55331
HPRD ID		17844
Ensembl ID
Uniprot IDs		B7Z2Q2 B7Z2V2 F5GYA0 Q9NUN7
PDB IDs
Enriched GO Terms of Interacting Partners?		Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Negative Regulation Of Mitotic Recombination Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Spindle Midzone Assembly Resolution Of Meiotic Recombination Intermediates Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Nuclear-transcribed MRNA Poly(A) Tail Shortening Isotype Switching Metaphase Plate Congression Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Establishment Of Chromosome Localization Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Reciprocal Meiotic Recombination B Cell Activation Involved In Immune Response Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Synapsis Mismatch Repair Homologous Chromosome Segregation Male Meiosis Immunoglobulin Production Regulation Of DNA Recombination Oogenesis MRNA 3'-end Processing Meiotic Chromosome Segregation Spindle Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of DNA Metabolic Process RNA 3'-end Processing Meiosis I Female Gamete Generation Spindle Organization Nuclear-transcribed MRNA Catabolic Process Double-strand Break Repair Leukocyte Activation Involved In Immune Response B Cell Activation MRNA Catabolic Process Meiotic Nuclear Division Immunoglobulin Mediated Immune Response B Cell Mediated Immunity RNA Catabolic Process Intrinsic Apoptotic Signaling Pathway Meiotic Cell Cycle Chromosome Segregation
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