P3H2

Description		prolyl 3-hydroxylase 2
Image		No pdb structure
GO Annotations	Cellular Component	Basement Membrane Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Cytosol Sarcoplasmic Reticulum
	Molecular Function	Iron Ion Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Procollagen-proline 3-dioxygenase Activity L-ascorbic Acid Binding Metal Ion Binding Dioxygenase Activity
	Biological Process	Negative Regulation Of Cell Population Proliferation Peptidyl-proline Hydroxylation Collagen Metabolic Process
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Ascorbic acid Proline
Diseases
GWAS		Congenital heart disease (septal defects) ( 33201861)
Novel Interacting Genes		1 novel interacting genes: FXR1
Interacting Genes		1 interacting genes: UBC
Entrez ID		55214
HPRD ID		17270
Ensembl ID		ENSG00000090530
Uniprot IDs		Q8IVL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Tag Activity Costamere RNA Strand Annealing Activity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Long-term Synaptic Potentiation Ribonucleoprotein Granule Nuclear Pore Localization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Nuclear Pore Organization Positive Regulation Of MiRNA-mediated Gene Silencing Intracellular Membraneless Organelle Nuclear Pore Complex Assembly Translation Regulator Activity Regulation Of Circadian Sleep/wake Cycle, Sleep Pore Complex Assembly Skeletal Muscle Organ Development MRNA 3'-UTR AU-rich Region Binding Dentate Gyrus Development Regulation Of Circadian Sleep/wake Cycle Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Rho Protein Signal Transduction Cytoplasmic Translational Initiation Ribonucleoprotein Complex Binding Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Long-term Synaptic Potentiation Molecular Condensate Scaffold Activity Regulation Of Neuronal Synaptic Plasticity RNA Binding Negative Regulation Of Tumor Necrosis Factor Production Protein-containing Complex Localization Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Endocytic Vesicle Membrane Positive Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Behavior Negative Regulation Of MRNA Catabolic Process Translational Initiation Cytoplasmic Ribonucleoprotein Granule
Tagcloud ?