INTS10

Gene Name		integrator complex subunit 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integrator Complex
	Molecular Function	Protein Binding
	Biological Process	SnRNA Processing
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Hypertriglyceridemia ( 23505323)
Protein-protein Interactions		1 interactors: RAF1
Entrez ID		55174
HPRD ID		07686
Ensembl ID		ENSG00000104613
Uniprot IDs		Q9NVR2
PDB IDs
Enriched GO Terms of Interacting Partners?		Death-inducing Signaling Complex Assembly Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Activation Of Adenylate Cyclase Activity Positive Regulation Of Adenylate Cyclase Activity Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Positive Regulation Of Lyase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Adenylate Cyclase Activity Positive Regulation Of CAMP Biosynthetic Process Activation Of MAPKK Activity Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Somatic Stem Cell Maintenance Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Peptidyl-serine Phosphorylation Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Protein Complex Assembly Insulin Receptor Signaling Pathway Stem Cell Maintenance Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Platelet Activation Response To Fibroblast Growth Factor Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Ras Protein Signal Transduction Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway MAPK Cascade Stem Cell Development Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Endopeptidase Activity Fc Receptor Signaling Pathway Activation Of Protein Kinase Activity Negative Regulation Of Peptidase Activity Signal Transduction By Phosphorylation Response To Insulin
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