PNPO

Description		pyridoxamine 5'-phosphate oxidase
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GO Annotations	Cellular Component	Mitochondrion Cytosol
	Molecular Function	Pyridoxamine Phosphate Oxidase Activity Protein Binding FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors Pyridoxal Phosphate Binding Protein Homodimerization Activity
	Biological Process	Pyridoxine Biosynthetic Process Pyridoxamine Metabolic Process Pyridoxal Phosphate Metabolic Process Pyridoxal Phosphate Biosynthetic Process
Pathways		Vitamin B6 activation to pyridoxal phosphate
Drugs		Pyridoxal phosphate Flavin mononucleotide Mercaptoethanol
Diseases
GWAS		Body mass index ( 26426971) Generalized epilepsy ( 22949513 30531953)
Interacting Genes		4 interacting genes: AGTRAP APP CMTM5 LIME1
Entrez ID		55163
HPRD ID		04476
Ensembl ID		ENSG00000108439
Uniprot IDs		Q9NVS9 V9HW45
PDB IDs		1NRG 3HY8 6H00 8QYT 8QYW 8ROS
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Calcium Ion Transport Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling B Cell Receptor Complex Angiotensin Type II Receptor Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Monoatomic Cation Transmembrane Transport Axon Choice Point Recognition Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Chemotaxis Cellular Response To Manganese Ion Extracellular Space Regulation Of Metal Ion Transport Antifungal Humoral Response Locomotion Nuclear Envelope Lumen
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