WRAP53

Description		WD repeat containing antisense to TP53
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Chromosome Telomerase Holoenzyme Complex Cytosol Cajal Body Nuclear Body Site Of Double-strand Break
	Molecular Function	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Histone Binding Identical Protein Binding Protein-containing Complex Binding Protein-folding Chaperone Binding Telomerase RNA Binding Protein Carrier Chaperone RNA Folding Chaperone
	Biological Process	DNA Repair DNA Damage Response Telomere Maintenance Via Telomerase Cajal Body Organization Telomere Formation Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase RNA Folding Positive Regulation Of DNA Repair ScaRNA Localization To Cajal Body Telomerase RNA Localization To Cajal Body Positive Regulation Of Establishment Of Protein Localization To Telomere Protein Localization To Cajal Body Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		Telomere Extension By Telomerase Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Cognitive function ( 28093568)
Interacting Genes		4 interacting genes: DSCR9 RECQL4 UBAP2 VAC14
Entrez ID		55135
HPRD ID		07670
Ensembl ID		ENSG00000141499
Uniprot IDs		Q9BUR4
PDB IDs		7BGB 7TRC 7V9A 8OUE 8OUF
Enriched GO Terms of Interacting Partners?		Telomeric D-loop Binding Catalytic Activity, Acting On DNA Four-way Junction Helicase Activity Telomeric D-loop Disassembly Bubble DNA Binding DNA/DNA Annealing Activity Oxidized Purine DNA Binding PAS Complex Presynaptic Endosome Telomeric Loop Disassembly 3'-5' DNA Helicase Activity
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