SLC6A15

Description		solute carrier family 6 member 15
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Neutral L-amino Acid:sodium Symporter Activity Proline:sodium Symporter Activity Neurotransmitter Transmembrane Transporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Symporter Activity Branched-chain Amino Acid:sodium Symporter Activity Transmembrane Transporter Activity
	Biological Process	Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Neurotransmitter Transport Amino Acid Transport Neutral Amino Acid Transport L-leucine Transport Proline Transport Sodium Ion Transmembrane Transport Carboxylic Acid Transmembrane Transport
Pathways		Amino acid transport across the plasma membrane SLC-mediated transport of neurotransmitters
Drugs
Diseases
GWAS		Atopic march ( 26542096) Behavioural disinhibition (generation interaction) ( 23942779) Cognitive decline rate in late mild cognitive impairment ( 26252872) Glaucoma (primary open-angle) ( 29891935 33627673) Major depressive disorder ( 27479909) Metabolite levels ( 23823483) PR interval ( 32439900) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Novel Interacting Genes		1 novel interacting genes: BBS5
Interacting Genes		2 interacting genes: LNX1 SNCA
Entrez ID		55117
HPRD ID		12141
Ensembl ID		ENSG00000072041
Uniprot IDs		A0A7P0T8I1 Q8IXG2 Q9H2J7 Q9NW50
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Vesicle Localization Establishment Of Vesicle Localization Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Serotonin Uptake Postsynapse Transporter Regulator Activity Establishment Of Organelle Localization Negative Regulation Of Chaperone-mediated Autophagy Regulation Of Serotonin Uptake Synapse Organization Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Response To Iron(II) Ion BBSome Regulation Of Chaperone-mediated Autophagy Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Dopamine Biosynthetic Process Negative Regulation Of Cellular Respiration Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Organelle Localization Cell Junction Organization Positive Regulation Of Receptor Recycling Regulation Of SNARE Complex Assembly Negative Regulation Of Microtubule Polymerization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport Synaptic Transmission, Dopaminergic Response To Epinephrine Regulation Of Hydrogen Peroxide Metabolic Process Platelet Alpha Granule Membrane Synaptic Vesicle Priming Response To Magnesium Ion
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