ANO1

Description		anoctamin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Membrane Apical Plasma Membrane Chloride Channel Complex Cell Projection Synapse Extracellular Exosome Presynapse
	Molecular Function	Signaling Receptor Binding Calcium-activated Cation Channel Activity Intracellularly Calcium-gated Chloride Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Iodide Transmembrane Transporter Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Dimerization Activity
	Biological Process	Monoatomic Ion Transport Chloride Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Iodide Transport Monoatomic Ion Transmembrane Transport Cellular Response To Heat Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Mucus Secretion Protein Localization To Membrane Monoatomic Cation Transmembrane Transport Glial Cell Projection Elongation Cellular Response To Peptide Chloride Transmembrane Transport
Pathways		Stimuli-sensing channels Induction of Cell-Cell Fusion
Drugs		Crofelemer
Diseases
GWAS		A body shape index ( 34021172) Appendicular lean mass ( 33097823) Basophil count ( 32888494) Birth weight ( 31043758) Childhood ear infection ( 27182965 28928442) Diastolic blood pressure ( 30224653) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Haemorrhoidal disease ( 33888516) Monobrow ( 27182965) Survival in rectal cancer ( 25866641) Systolic blood pressure ( 30578418) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Novel Interacting Genes		1 novel interacting genes: SHANK2
Interacting Genes		2 interacting genes: COPB1 TRIM23
Entrez ID		55107
HPRD ID		18202
Ensembl ID		ENSG00000131620
Uniprot IDs		Q5XXA6 Q9NW72
PDB IDs
Enriched GO Terms of Interacting Partners?
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