RADX

Description		RPA1 related single stranded DNA binding protein, X-linked
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GO Annotations	Cellular Component	Replication Fork Chromosome Nuclear Speck
	Molecular Function	DNA Binding Single-stranded DNA Binding RNA Binding Protein Binding
	Biological Process	Regulation Of DNA Repair Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: MLH1 PLEKHF2
Entrez ID		55086
HPRD ID		06513
Ensembl ID		ENSG00000147231
Uniprot IDs		Q6NSI4
PDB IDs		8U5Y 8U61
Enriched GO Terms of Interacting Partners?		Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Guanine/thymine Mispair Binding Male Meiosis Chromosome Segregation Homologous Chromosome Segregation MutLalpha Complex Female Meiosis Chromosome Segregation Mismatch Repair Complex Negative Regulation Of Mitotic Recombination Positive Regulation Of Isotype Switching To IgA Isotypes MutSalpha Complex Binding Regulation Of Mitotic Recombination Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Telomere Localization Mismatched DNA Binding Positive Regulation Of Isotype Switching To IgG Isotypes Spindle Midzone Assembly Somatic Hypermutation Of Immunoglobulin Genes Meiotic Chromosome Segregation Somatic Diversification Of Immune Receptors Via Somatic Mutation Regulation Of Isotype Switching To IgG Isotypes Resolution Of Meiotic Recombination Intermediates ATP-dependent DNA Damage Sensor Activity Nuclear-transcribed MRNA Poly(A) Tail Shortening Isotype Switching Homologous Chromosome Pairing At Meiosis Positive Regulation Of Isotype Switching Somatic Diversification Of Immunoglobulins Involved In Immune Response Reciprocal Meiotic Recombination Synaptonemal Complex Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Mismatch Repair Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Regulation Of Isotype Switching Nuclear Lumen Homologous Recombination Positive Regulation Of Immunoglobulin Mediated Immune Response Somatic Diversification Of Immunoglobulins Somatic Cell DNA Recombination Oogenesis Male Meiotic Nuclear Division Negative Regulation Of DNA Recombination Condensed Nuclear Chromosome Male Germ Cell Nucleus Nuclear Chromosome Segregation
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