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FKBP14
Gene Name
FK506 binding protein 14, 22 kDa
Image
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Molecular Function
Peptidyl-prolyl Cis-trans Isomerase Activity
Calcium Ion Binding
FK506 Binding
Biological Process
Protein Peptidyl-prolyl Isomerization
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Endoplasmic Reticulum Unfolded Protein Response
Cellular Protein Metabolic Process
Chaperone-mediated Protein Folding
Pathways
IRE1alpha activates chaperones
XBP1(S) activates chaperone genes
Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Estradiol levels (
22675492
)
Protein-protein Interactions
2 interactors:
GSK3B
POLR2E
Entrez ID
55033
HPRD ID
16898
Ensembl ID
ENSG00000106080
Uniprot IDs
Q9NWM8
PDB IDs
4DIP
Enriched GO Terms of Interacting Partners
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Regulation Of Gene Expression, Epigenetic
Stem Cell Development
Negative Regulation Of Type B Pancreatic Cell Development
Superior Temporal Gyrus Development
Stem Cell Differentiation
Re-entry Into Mitotic Cell Cycle
Negative Regulation Of Neuron Maturation
Hypermethylation Of CpG Island
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Cellular Response To Interleukin-3
Regulation Of Neuron Maturation
Negative Regulation Of Glycogen (starch) Synthase Activity
Protein Localization To Microtubule
Negative Regulation Of Dendrite Morphogenesis
Negative Regulation Of NFAT Protein Import Into Nucleus
ER Overload Response
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Muscle Hypertrophy
Regulation Of Glycogen (starch) Synthase Activity
Negative Regulation Of Cell Differentiation
Positive Regulation Of Protein Export From Nucleus
Innate Immune Response
Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Peptidyl-threonine Phosphorylation
Termination Of RNA Polymerase III Transcription
Transcription Elongation From RNA Polymerase III Promoter
Negative Regulation Of Dendrite Development
Regulation Of DNA Methylation
Myoblast Fusion
Protein Localization To Cytoskeleton
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Regulation Of Gene Expression By Genetic Imprinting
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Response To Lithium Ion
Regulation Of Cellular Response To Heat
Regulation Of Cardiac Muscle Hypertrophy
Regulation Of Protein Export From Nucleus
7-methylguanosine MRNA Capping
Transcription From RNA Polymerase I Promoter
Regulation Of Glycogen Biosynthetic Process
PiRNA Metabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Syncytium Formation
Genetic Imprinting
7-methylguanosine RNA Capping
Negative Regulation Of Epithelial Cell Differentiation
Immune Response
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