ACP3

Name	acid phosphatase 3
Structure
Novel Interactors	1 novel interactors: EPHB1
Interactors	2 interactors: ERBB2 SHBG
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Lysosome Lysosomal Membrane Multivesicular Body Cytosol Plasma Membrane Vesicle Membrane Membrane Secretory Granule Filopodium Golgi Cisterna Azurophil Granule Membrane Apical Part Of Cell Extracellular Exosome
	Molecular Function	Acid Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding 5'-nucleotidase Activity Hydrolase Activity Phosphatase Activity Choline Binding Thiamine Phosphate Phosphatase Activity Identical Protein Binding Protein Homodimerization Activity Lysophosphatidic Acid Phosphatase Activity Molecular Adaptor Activity
	Biological Process	Purine Nucleobase Metabolic Process Lipid Metabolic Process Thiamine Metabolic Process Nucleotide Metabolic Process Adenosine Metabolic Process Regulation Of Sensory Perception Of Pain Positive Regulation Of Adenosine Receptor Signaling Pathway
Pathways	Neutrophil degranulation
Drugs	(2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid Alpha-Benzyl-Aminobenzyl-Phosphonic Acid Sipuleucel-T
GWAS	No GWAS studies recorded
Entrez ID	55
HPRD ID	01378
Ensembl ID	ENSG00000014257
Uniprot IDs	P15309
PDB IDs	1CVI 1ND5 1ND6 2HPA 2L3H 2L77 2L79 2MG0 3PPD 7ZZV 8XJ4
GO Terms Enriched among Interactors ?	Transmembrane Receptor Protein Tyrosine Kinase Activity Optic Nerve Morphogenesis Negative Regulation Of Skeletal Muscle Cell Proliferation Negative Regulation Of Satellite Cell Differentiation Regulation Of ERK1 And ERK2 Cascade Neuron Projection Guidance Hindbrain Tangential Cell Migration Negative Regulation Of Skeletal Muscle Satellite Cell Proliferation Axon Guidance Protein Tyrosine Kinase Activity Negative Regulation Of Immature T Cell Proliferation In Thymus RNA Polymerase I Core Binding ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Immature T Cell Proliferation In Thymus ERBB2-ERBB4 Signaling Pathway Androgen Binding Skeletal Muscle Satellite Cell Activation Negative Regulation Of Immature T Cell Proliferation Negative Regulation Of Skeletal Muscle Cell Differentiation Protein Phosphorylation Phosphorylation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB2-EGFR Signaling Pathway ERBB4 Signaling Pathway Regulation Of Skeletal Muscle Cell Proliferation Transmembrane-ephrin Receptor Activity Neuron Projection Development Cell Migration In Hindbrain Axon Guidance Receptor Activity Immunological Synapse Formation Cranial Nerve Morphogenesis Dendritic Spine Development Protein Kinase Activity Regulation Of Skeletal Muscle Satellite Cell Proliferation Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Ephrin Receptor Activity Negative Regulation Of T Cell Differentiation In Thymus Semaphorin Receptor Complex Regulation Of Immature T Cell Proliferation In Thymus Filopodium Tip Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Dendritic Spine Morphogenesis Nervous System Development Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Enzyme-linked Receptor Protein Signaling Pathway Detection Of Temperature Stimulus Central Nervous System Projection Neuron Axonogenesis