ACSM5

Gene Name		acyl-CoA synthetase medium-chain family member 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix
	Molecular Function	ATP Binding GTP Binding Metal Ion Binding Butyrate-CoA Ligase Activity
	Biological Process	Fatty Acid Metabolic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Conjugation of salicylate with glycine Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Conjugation of carboxylic acids Amino Acid conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146)
Protein-protein Interactions		1 interactors: EP300
Entrez ID		54988
HPRD ID		08627
Ensembl ID		ENSG00000183549
Uniprot IDs		Q6NUN0
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H2B Acetylation N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Tubulin Deacetylation Positive Regulation By Host Of Viral Transcription N-terminal Protein Amino Acid Acetylation Regulation Of Androgen Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Viral Transcription Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Protein Deacetylation Histone H4 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Heat Positive Regulation Of Protein Binding Regulation Of Viral Transcription Positive Regulation Of Viral Process Positive Regulation Of Type I Interferon Production Somitogenesis Protein Stabilization Endoplasmic Reticulum Unfolded Protein Response Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Somite Development Cellular Response To Hypoxia Cellular Response To Unfolded Protein Cellular Response To Decreased Oxygen Levels ER-nucleus Signaling Pathway Regulation Of Type I Interferon Production Cellular Response To Oxygen Levels Cellular Response To Topologically Incorrect Protein Response To Heat Histone Acetylation Signal Transduction By P53 Class Mediator Segmentation G2/M Transition Of Mitotic Cell Cycle Internal Peptidyl-lysine Acetylation Positive Regulation Of Binding Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Response To Unfolded Protein Protein Acetylation Regulation Of Protein Stability Skeletal Muscle Tissue Development
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