PLAAT2

Description		phospholipase A and acyltransferase 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane
	Molecular Function	Phospholipase A2 Activity Protein Binding Phospholipase A1 Activity N-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity
	Biological Process	Lipid Metabolic Process Lipid Catabolic Process Phosphatidylethanolamine Acyl-chain Remodeling N-acylphosphatidylethanolamine Metabolic Process
Pathways		Acyl chain remodelling of PE
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: ASPH HPCAL1 NCALD UBAC1 UBQLN1 UBQLN2
Entrez ID		54979
HPRD ID		13670
Ensembl ID		ENSG00000133328
Uniprot IDs		Q9NWW9
PDB IDs		4DPZ
Enriched GO Terms of Interacting Partners?		Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of ERAD Pathway Positive Regulation Of Proteolysis Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Proteolysis Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Negative Regulation Of Store-operated Calcium Channel Activity Autophagosome Organization Peptidyl-aspartic Acid 3-dioxygenase Activity Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteasomal Protein Catabolic Process Calcium Ion Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Calcium-mediated Signaling Negative Regulation Of Clathrin-dependent Endocytosis Vacuole Organization Activation Of Store-operated Calcium Channel Activity Regulation Of Cell Communication Positive Regulation Of Protein Metabolic Process Regulation Of Macroautophagy Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Store-operated Calcium Channel Activity Positive Regulation Of Protein Catabolic Process Regulation Of Calcium Ion Transport Clathrin Coat Of Trans-Golgi Network Vesicle Cortical Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Sarcoplasmic Reticulum Lumen Junctional Sarcoplasmic Reticulum Membrane Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Toll-like Receptor 3 Signaling Pathway Autophagy Positive Regulation Of Calcium Ion Transport Into Cytosol Aggrephagy Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Negative Regulation Of Receptor Internalization Regulation Of Metal Ion Transport Proteasome Binding Regulation Of Clathrin-dependent Endocytosis
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