SSH3

Description		slingshot protein phosphatase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton
	Molecular Function	Actin Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Phosphatase Activity
	Biological Process	Actin Cytoskeleton Organization Negative Regulation Of Actin Filament Polymerization
Pathways
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) HDL cholesterol levels ( 32203549) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		1 novel interacting genes: TMEM216
Interacting Genes		6 interacting genes: ACTB APP CFL1 LIMK1 MTDH NCK2
Entrez ID		54961
HPRD ID		09488
Ensembl ID		ENSG00000172830
Uniprot IDs		Q8TE77
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Multicellular Organismal Process Regulation Of Supramolecular Fiber Organization Regulation Of Dendritic Spine Maintenance Cell Projection Organization Supramolecular Fiber Organization Positive Regulation Of Developmental Process Lamellipodium Positive Regulation Of Cytoskeleton Organization Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Actin Filament Organization Regulation Of Actin Filament Organization Positive Regulation Of Immune System Process Regulation Of Multicellular Organismal Process Axon Actin Cytoskeleton Organization Positive Regulation Of Cell Activation Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Amyloid-beta Complex Growth Cone Lamellipodium Synaptic Membrane Regulation Of Response To Calcium Ion Regulation Of Developmental Growth Amylin Binding Positive Regulation Of Toll Signaling Pathway Cofilin-actin Rod Rho Protein Signal Transduction Negative Regulation Of Unidimensional Cell Growth Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Establishment Of Cell Polarity Regulating Cell Shape Positive Regulation Of Barbed-end Actin Filament Capping Regulation Of Actin Filament-based Process Positive Regulation Of Protein Localization To Cell Leading Edge Actin Filament-based Process Focal Adhesion Response To Interleukin-1 Positive Regulation Of Cellular Component Organization Regulation Of Response To Endoplasmic Reticulum Stress Cell Junction Organization Regulation Of Organelle Organization Positive Regulation Of Cell Adhesion Regulation Of Norepinephrine Uptake Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Cell Projection
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