COMMD4

Description		COMM domain containing 4
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding
	Biological Process	Signal Transduction
Pathways		Neddylation
Drugs
Diseases
GWAS		Microalbuminuria ( 31511532) Serum uric acid levels ( 30993211) Urate levels ( 31578528) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		4 interacting genes: BUB1B COMMD1 H2AC4 TBCD
Entrez ID		54939
HPRD ID		13083
Ensembl ID		ENSG00000140365
Uniprot IDs		A0A0B4J287 H3BQF2 Q9H0A8
PDB IDs		8F2R 8F2U 8P0W
Enriched GO Terms of Interacting Partners?		Protein Localization To Chromosome, Centromeric Region Protein Localization To Chromosome Positive Regulation Of Cholesterol Import Mitotic Checkpoint Complex Meiotic Sister Chromatid Cohesion, Centromeric Negative Regulation Of Hypoxia-inducible Factor-1alpha Signaling Pathway Positive Regulation Of Endosome To Plasma Membrane Protein Transport Regulation Of Plasma Lipoprotein Particle Levels Regulation Of Cholesterol Import Metaphase/anaphase Transition Of Mitotic Cell Cycle Metaphase/anaphase Transition Of Cell Cycle Post-chaperonin Tubulin Folding Pathway Sodium Channel Inhibitor Activity Positive Regulation Of Endocytic Recycling Tubulin Complex Assembly Plasma Membrane To Endosome Transport Negative Regulation Of Sodium Ion Transmembrane Transport Meiotic Sister Chromatid Cohesion Negative Regulation Of Protein Localization To Cell Surface Adherens Junction Assembly Negative Regulation Of Microtubule Polymerization Negative Regulation Of Sodium Ion Transport Negative Regulation Of Cellular Response To Hypoxia Low-density Lipoprotein Particle Clearance Intracellular Protein Localization Outer Kinetochore CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Regulation Of Endocytic Recycling Cul2-RING Ubiquitin Ligase Complex Copper Ion Homeostasis Positive Regulation Of Protein Localization To Cell Surface Anaphase-promoting Complex Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cellular Response To Hypoxia Protein Localization To Organelle Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Centrosome Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Protein Localization To Cell Surface Phosphatidic Acid Binding Plasma Lipoprotein Particle Clearance Positive Regulation Of Cholesterol Transport Negative Regulation Of Cellular Component Organization Negative Regulation Of Mitotic Nuclear Division Chromosome Beta-tubulin Binding Regulation Of Sodium Ion Transmembrane Transport
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