CDKAL1

Gene Name		CDK5 regulatory subunit associated protein 1-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function N6-threonylcarbomyladenosine Methylthiotransferase Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Biological_process TRNA Methylthiolation Maintenance Of Translational Fidelity
Pathways
Drugs
Diseases
GWAS		Birth weight ( 23202124) Body mass index ( 22344219 22344221) Bone mineral density ( 22504420) Crohn's disease ( 18587394 21102463) Diabetes (gestational) ( 22233651) Glycated hemoglobin levels ( 22290723) Glycemic traits ( 23575436) Ileal carcinoids ( 21139019) Obesity-related traits ( 23251661) Type 2 diabetes ( 21490949 18372903 18711366 22693455 17554300 22961080 20581827 19401414 17463246 17463248 17463249 17460697) Type 2 diabetes and other traits ( 19734900)
Protein-protein Interactions		1 interactors: LCK
Entrez ID		54901
HPRD ID		13022
Ensembl ID		ENSG00000145996
Uniprot IDs		Q5VV42
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Gamma-delta T Cell Activation Positive Regulation Of Uterine Smooth Muscle Contraction Regulation Of Gamma-delta T Cell Differentiation Cellular Zinc Ion Homeostasis Zinc Ion Homeostasis Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Positive Regulation Of T Cell Receptor Signaling Pathway Regulation Of Defense Response To Virus By Virus Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol Peptidyl-tyrosine Autophosphorylation Regulation Of Sequestering Of Calcium Ion B Cell Receptor Signaling Pathway Calcium Ion Transport Into Cytosol Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of T Cell Receptor Signaling Pathway Cytosolic Calcium Ion Transport Response To Zinc Ion Regulation Of Smooth Muscle Contraction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of JAK-STAT Cascade T Cell Costimulation Regulation Of Defense Response To Virus Positive Regulation Of T Cell Differentiation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of JAK-STAT Cascade Positive Regulation Of Lymphocyte Differentiation Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation T Cell Receptor Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of T Cell Differentiation Positive Regulation Of Cysteine-type Endopeptidase Activity Response To Hydrogen Peroxide Positive Regulation Of Endopeptidase Activity Antigen Receptor-mediated Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Peptidase Activity Transition Metal Ion Homeostasis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Lymphocyte Differentiation T Cell Differentiation Regulation Of Muscle Contraction Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway
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