DCAF16

Description		DDB1 and CUL4 associated factor 16
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding
	Biological Process	Protein Ubiquitination
Pathways		Neddylation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Height ( 34270706) Hip circumference adjusted for BMI ( 34021172) Offspring birth weight ( 31043758)
Interacting Genes		3 interacting genes: CUL4B PRMT1 PRMT6
Entrez ID		54876
HPRD ID		07891
Ensembl ID		ENSG00000163257
Uniprot IDs		Q9NXF7
PDB IDs		8G46 8OV6
Enriched GO Terms of Interacting Partners?		Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine N-methyltransferase Activity Histone Methyltransferase Activity Regulation Of Megakaryocyte Differentiation DNA Repair DNA Metabolic Process DNA Damage Response GATOR1 Complex Binding Histone H2AR3 Methyltransferase Activity Methyltransferase Activity Histone H3R2 Methyltransferase Activity Methylation Regulation Of Myeloid Cell Differentiation Histone Arginine N-methyltransferase Activity N-methyltransferase Activity Regulation Of Protein Metabolic Process Cellular Response To Stress Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine Histone H4 Methyltransferase Activity Cellular Response To Methionine Cul4B-RING E3 Ubiquitin Ligase Complex Nucleic Acid Metabolic Process Regulation Of Hemopoiesis UV-damage Excision Repair Methylosome Protein Methyltransferase Activity Cul4A-RING E3 Ubiquitin Ligase Complex Cullin-RING Ubiquitin Ligase Complex Nucleobase-containing Compound Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Negative Regulation Of Protein Metabolic Process S-adenosyl-L-methionine Binding Chromatin Remodeling Histone H3 Methyltransferase Activity Methyl-CpG Binding Viral Protein Processing Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of P38MAPK Cascade Cul4-RING E3 Ubiquitin Ligase Complex Astrocyte Differentiation Positive Regulation Of Protein Metabolic Process Protein Methylation Negative Regulation Of JNK Cascade Positive Regulation Of Erythrocyte Differentiation
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