CNTLN

Gene Name		centlein, centrosomal protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centriole Membrane Extracellular Vesicular Exosome
	Molecular Function	Phosphorelay Sensor Kinase Activity Protein Kinase Binding Protein Domain Specific Binding Protein Binding, Bridging
	Biological Process	Phosphorelay Signal Transduction System Centriole-centriole Cohesion Signal Transduction By Phosphorylation Protein Localization To Organelle
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 19648919) Response to amphetamines ( 22952603)
Protein-protein Interactions		2 interactors: BRCA1 UBC
Entrez ID		54875
HPRD ID		10800
Ensembl ID		ENSG00000044459
Uniprot IDs		C9J1F9 Q9NXG0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Signal Transduction In Response To DNA Damage Regulation Of Cell Cycle Arrest Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination DNA Damage Checkpoint Protein Polyubiquitination Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Cell Cycle Process Cell Cycle Checkpoint Positive Regulation Of Cell Cycle Positive Regulation Of Histone H3-K9 Acetylation Apoptotic Signaling Pathway Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Positive Regulation Of Cytokine Production Negative Regulation Of Cell Cycle Cellular Response To Indole-3-methanol Regulation Of Cell Cycle Process Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Regulation Of Cytokine Production Protein Ubiquitination Protein K6-linked Ubiquitination Cellular Response To Cytokine Stimulus DNA Repair Protein Modification By Small Protein Conjugation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Viral Protein Processing Response To Cytokine Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Histone Methylation Cellular Response To DNA Damage Stimulus Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Negative Regulation Of Protein Metabolic Process
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