ZNF280D

Description		zinc finger protein 280D
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Glaucoma (primary open-angle) ( 29891935) Hand grip strength ( 29691431) Intraocular pressure ( 29785010 30054594 31959993) Platelet count ( 27863252 32888494) Platelet distribution width ( 27863252 32888494) Triglyceride levels ( 32203549)
Interacting Genes		3 interacting genes: BRCA1 CBX3 CBX5
Entrez ID		54816
HPRD ID		15448
Ensembl ID		ENSG00000137871
Uniprot IDs		Q6N043
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Heterochromatin Formation Epigenetic Regulation Of Gene Expression Pericentric Heterochromatin Site Of DNA Damage Heterochromatin Chromatin Remodeling DNA Damage Response Chromatin Organization Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Negative Regulation Of Gene Expression Chromosome, Centromeric Region Chromosome, Telomeric Region Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nuclear Envelope Negative Regulation Of RNA Metabolic Process Chromatin Lock Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process BRCA1-B Complex Senescence-associated Heterochromatin Focus Cellular Response To Stress Cellular Response To Indole-3-methanol Nuclear Ubiquitin Ligase Complex BRCA1-C Complex Response To Indole-3-methanol Identical Protein Binding Negative Regulation Of Centriole Replication BRCA1-A Complex Ubiquitin-modified Histone Reader Activity Ribonucleoprotein Complex Enzyme Binding Negative Regulation Of Centrosome Duplication Negative Regulation Of Macromolecule Biosynthetic Process Lateral Element Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Gamma-tubulin Ring Complex Negative Regulation Of Biosynthetic Process DNA Strand Resection Involved In Replication Fork Processing DNA Repair Complex Random Inactivation Of X Chromosome Chromatin Binding Chromocenter XY Body Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Histone Methyltransferase Binding Condensed Chromosome, Centromeric Region Histone H3K9me2/3 Reader Activity
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