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ZNF280D
Name
zinc finger protein 280D
Structure
No pdb structure
Interactors
3 interactors:
BRCA1
CBX3
CBX5
GO Annotations
Cellular Component
Nucleus
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Biological Process
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
GWAS
Body fat mass (
28552196
)
Glaucoma (primary open-angle) (
29891935
)
Hand grip strength (
29691431
)
Intraocular pressure (
29785010
30054594
31959993
)
Platelet count (
27863252
32888494
)
Platelet distribution width (
27863252
32888494
)
Triglyceride levels (
32203549
)
Entrez ID
54816
HPRD ID
15448
Ensembl ID
ENSG00000137871
Uniprot IDs
Q6N043
PDB IDs
Not available
GO Terms Enriched among Interactors
?
Negative Regulation Of Gene Expression, Epigenetic
Heterochromatin Formation
Epigenetic Regulation Of Gene Expression
Pericentric Heterochromatin
Site Of DNA Damage
Heterochromatin
Chromatin Remodeling
DNA Damage Response
Chromatin Organization
Histone H2AK127 Ubiquitin Ligase Activity
Histone H2AK129 Ubiquitin Ligase Activity
BRCA1-BARD1 Complex
Negative Regulation Of Gene Expression
Chromosome, Centromeric Region
Chromosome, Telomeric Region
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nuclear Envelope
Negative Regulation Of RNA Metabolic Process
Chromatin Lock Complex
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
BRCA1-B Complex
Senescence-associated Heterochromatin Focus
Cellular Response To Stress
Cellular Response To Indole-3-methanol
Nuclear Ubiquitin Ligase Complex
BRCA1-C Complex
Response To Indole-3-methanol
Identical Protein Binding
Negative Regulation Of Centriole Replication
BRCA1-A Complex
Ubiquitin-modified Histone Reader Activity
Ribonucleoprotein Complex
Enzyme Binding
Negative Regulation Of Centrosome Duplication
Negative Regulation Of Macromolecule Biosynthetic Process
Lateral Element
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Gamma-tubulin Ring Complex
Negative Regulation Of Biosynthetic Process
DNA Strand Resection Involved In Replication Fork Processing
DNA Repair Complex
Random Inactivation Of X Chromosome
Chromatin Binding
Chromocenter
XY Body
Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation
Histone Methyltransferase Binding
Condensed Chromosome, Centromeric Region
Histone H3K9me2/3 Reader Activity