TRIT1

Description		tRNA isopentenyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Protein Binding ATP Binding Zinc Ion Binding Transferase Activity Metal Ion Binding TRNA Dimethylallyltransferase Activity
	Biological Process	TRNA Modification TRNA Processing Mitochondrial TRNA Modification
Pathways		tRNA modification in the nucleus and cytosol tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: COL6A3
Interacting Genes		6 interacting genes: AKT1 ANKS1A HGH1 OGT SHE SMYD3
Entrez ID		54802
HPRD ID		18226
Ensembl ID		ENSG00000043514
Uniprot IDs		Q3T7C7 Q53F11 Q9H3H1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Carbohydrate Homeostasis Response To Rapamycin Positive Regulation Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nitric-oxide Synthase Regulator Activity Glucose Homeostasis Regulation Of Proteasomal Protein Catabolic Process TOR Signaling Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Negative Regulation Of SREBP Signaling Pathway Negative Regulation Of Protein Ubiquitination Response To Insulin-like Growth Factor Stimulus Cytoplasmic Translation Negative Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of TORC2 Signaling TRNA Stabilization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Regulation Of Protein Localization To Cell Periphery Potassium Channel Activator Activity Regulation Of Protein Ubiquitination Mammalian Oogenesis Stage RNA (guanine-N7)-methylation Response To UV Negative Regulation Of Translational Initiation Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of TORC1 Signaling Phosphatidylinositol-3,4,5-trisphosphate Binding Negative Regulation Of Fatty Acid Transport Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Cellular Response To Peptide Regulation Of Glucose Metabolic Process Response To Hormone Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of TOR Signaling Maintenance Of Protein Location In Mitochondrion Negative Regulation Of Proteolysis Negative Regulation Of Translation TRNA (guanine-N7)-methylation Response To Ketone Activation-induced Cell Death Of T Cells Positive Regulation Of Translational Initiation Regulation Of Long-chain Fatty Acid Import Into Cell TORC2 Complex Binding Regulation Of Protein Localization To Membrane Response To Insulin Cellular Response To Rapamycin Positive Regulation Of Translation Peripheral Nervous System Myelin Maintenance
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