GRAMD1C

Description		GRAM domain containing 1C
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Organelle Membrane Contact Site Endoplasmic Reticulum-plasma Membrane Contact Site
	Molecular Function	Protein Binding Lipid Binding Cholesterol Binding Cholesterol Transfer Activity
	Biological Process	Lipid Transport Intracellular Sterol Transport Cellular Response To Cholesterol
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Lateral ventricle temporal horn volume ( 31530798)
Novel Interacting Genes		1 novel interacting genes: TIGIT
Interacting Genes		3 interacting genes: APP CD151 CD72
Entrez ID		54762
HPRD ID		13187
Ensembl ID		ENSG00000178075
Uniprot IDs		B3KUR5 Q8IYS0
PDB IDs		6GN5
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Signaling Receptor Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Integrin Binding Cell Surface Regulation Of Immune Response Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Cell Adhesion Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Endocytosis Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding
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