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PPAT
Gene Name
phosphoribosyl pyrophosphate amidotransferase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Molecular Function
Amidophosphoribosyltransferase Activity
Metal Ion Binding
4 Iron, 4 Sulfur Cluster Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Kidney Development
Purine Nucleobase Metabolic Process
Purine Nucleotide Biosynthetic Process
'de Novo' IMP Biosynthetic Process
Glutamine Catabolic Process
Lactation
Purine Nucleobase Biosynthetic Process
Nucleoside Metabolic Process
Purine Ribonucleoside Monophosphate Biosynthetic Process
Organ Regeneration
Cellular Response To Insulin Stimulus
Cellular Response To Drug
Small Molecule Metabolic Process
Protein Homotetramerization
Nucleobase-containing Small Molecule Metabolic Process
Maternal Process Involved In Female Pregnancy
Pathways
Purine ribonucleoside monophosphate biosynthesis
Purine metabolism
Metabolism of nucleotides
Drugs
L-Glutamine
Diseases
GWAS
Protein-protein Interactions
2 interactors:
ATXN1
EPT1
Entrez ID
5471
HPRD ID
01402
Ensembl ID
ENSG00000128059
Uniprot IDs
A8K4H7
Q06203
Q59G63
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Phosphatidylethanolamine Biosynthetic Process
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