PPAT

Description		phosphoribosyl pyrophosphate amidotransferase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Catalytic Activity Amidophosphoribosyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Purine Nucleotide Biosynthetic Process GMP Biosynthetic Process 'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process 'de Novo' AMP Biosynthetic Process 'de Novo' XMP Biosynthetic Process
Pathways		Purine ribonucleoside monophosphate biosynthesis
Drugs		L-Glutamine Mercaptopurine Dasatinib
Diseases
GWAS
Interacting Genes		4 interacting genes: ATXN1 CEBPA OGT SELENOI
Entrez ID		5471
HPRD ID		01402
Ensembl ID		ENSG00000128059
Uniprot IDs		A8K4H7 Q06203 Q59G63
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromatin DNA Binding Nuclear Matrix Protein-containing Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Nutrient Response To Vitamin B2 Memory C/EBP Complex Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Proteolysis Carbohydrate Homeostasis CHOP-C/EBP Complex Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Ubiquitin-dependent Protein Catabolic Process Glucose Homeostasis Regulation Of Proteasomal Protein Catabolic Process Protein O-acetylglucosaminyltransferase Activity Ethanolaminephosphotransferase Activity White Fat Cell Proliferation POZ Domain Binding Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Learning Or Memory Negative Regulation Of DNA-templated Transcription Response To Phenylpropanoid Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Positive Regulation Of Developmental Process Fat Cell Proliferation Poly(G) Binding Negative Regulation Of RNA Metabolic Process Cognition Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Transcription By Glucose Negative Regulation Of Nucleobase-containing Compound Metabolic Process Urea Metabolic Process HMG Box Domain Binding Regulation Of Protein Catabolic Process Urea Cycle Macromolecule Biosynthetic Process STAT Family Protein Binding Nuclear Inclusion Body NSL Complex
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