PPEF2

Gene Name		protein phosphatase, EF-hand calcium binding domain 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm
	Molecular Function	Protein Serine/threonine Phosphatase Activity Iron Ion Binding Calcium Ion Binding Protein Binding Manganese Ion Binding Hsp70 Protein Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Hsp90 Protein Binding
	Biological Process	Protein Dephosphorylation Visual Perception Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of MAP Kinase Activity Negative Regulation Of MAPK Cascade Regulation Of JUN Kinase Activity Detection Of Stimulus Involved In Sensory Perception
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CALM1 CALM2 CALM3
Entrez ID		5470
HPRD ID		03771
Ensembl ID		ENSG00000156194
Uniprot IDs		O14830
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine Positive Regulation Of Adenylate Cyclase Activity Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Nitric-oxide Synthase Activity Response To Mineralocorticoid Substantia Nigra Development Positive Regulation Of Oxidoreductase Activity Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Positive Regulation Of Lyase Activity Positive Regulation Of Dephosphorylation Negative Regulation Of Ion Transmembrane Transport Response To Amine Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Ion Transmembrane Transporter Activity
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