POU6F1

Name	POU class 6 homeobox 1
Structure
Interactors	3 interactors: ACOT7 ERBB2 NFYC
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Heart Development Muscle Organ Development
GWAS	Adult body size ( 32376654 ) Cisplatin-induced ototoxicity ( 28039263 ) Mean corpuscular hemoglobin ( 32888494 )
Entrez ID	5463
HPRD ID	17883
Ensembl ID	ENSG00000184271
Uniprot IDs	B3KT91 Q14863
PDB IDs	3D1N
GO Terms Enriched among Interactors ?	Negative Regulation Of Immature T Cell Proliferation In Thymus RNA Polymerase I Core Binding ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Immature T Cell Proliferation In Thymus ERBB2-ERBB4 Signaling Pathway CCAAT-binding Factor Complex Long-chain Fatty Acyl-CoA Binding Medium-chain Fatty Acid Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Palmitic Acid Biosynthetic Process Fatty-acyl-CoA Catabolic Process Medium-chain Fatty-acyl-CoA Metabolic Process Negative Regulation Of Immature T Cell Proliferation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB2-EGFR Signaling Pathway Protein Heterodimerization Activity ERBB4 Signaling Pathway Thiolester Hydrolase Activity Medium-chain Fatty Acid Metabolic Process Coenzyme A Biosynthetic Process Negative Regulation Of T Cell Differentiation In Thymus Semaphorin Receptor Complex Regulation Of Immature T Cell Proliferation In Thymus Long-chain Fatty Acyl-CoA Hydrolase Activity Fatty-acyl-CoA Binding Coenzyme A Metabolic Process Fatty Acyl-CoA Hydrolase Activity Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Motor Neuron Axon Guidance Peripheral Nervous System Development Regulation Of T Cell Differentiation In Thymus ERBB2 Signaling Pathway Positive Regulation Of Protein Targeting To Membrane Long-chain Fatty-acyl-CoA Metabolic Process Positive Regulation Of Rho Protein Signal Transduction Protein Localization To Postsynapse Regulation Of Protein Targeting To Membrane Protein Localization To Postsynaptic Membrane Positive Regulation Of Transcription By RNA Polymerase I Myelin Sheath Positive Regulation Of MAP Kinase Activity Neuromuscular Junction Development Long-chain Fatty Acid Biosynthetic Process Carboxylic Ester Hydrolase Activity Oligodendrocyte Differentiation Regulation Of Transcription By RNA Polymerase I