UGT1A9

Description		UDP glucuronosyltransferase family 1 member A9
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Retinoic Acid Binding Enzyme Inhibitor Activity Protein Binding UDP-glycosyltransferase Activity Glucuronosyltransferase Activity Transferase Activity Glycosyltransferase Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Liver Development Lipid Metabolic Process Xenobiotic Metabolic Process Flavonoid Metabolic Process Retinoic Acid Metabolic Process Negative Regulation Of Fatty Acid Metabolic Process Flavone Metabolic Process
Pathways		Glucuronidation PPARA activates gene expression Aspirin ADME Paracetamol ADME
Drugs		Niflumic acid Phenolphthalein
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732626) Bilirubin levels ( 32084209) Hair greying ( 26926045) Liver disease biomarker ( 30576415) Low density lipoprotein cholesterol levels ( 32154731) N-desmethylclozapine concentration in schizophrenia ( 32555152) Neuroblastoma or malignant cutaneous melanoma ( 31605138) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 23093944 33031748) Total bilirubin levels ( 29403010) Total bilirubin levels in HIV-1 infection ( 25884002)
Interacting Genes		1 interacting genes: GLP1R
Entrez ID		54600
HPRD ID		07073
Ensembl ID		ENSG00000241119
Uniprot IDs		O60656 Q5DSZ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Glucagon-like Peptide 1 Receptor Activity Glucagon Receptor Activity Response To Psychosocial Stress Post-translational Protein Targeting To Membrane, Translocation Cellular Response To Glucagon Stimulus Activation Of Adenylate Cyclase Activity Positive Regulation Of Lyase Activity Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Cyclase Activity Response To Glucagon Intracellular Protein Transmembrane Transport Positive Regulation Of Blood Pressure Peptide Hormone Binding G Protein-coupled Peptide Receptor Activity Negative Regulation Of Blood Pressure Protein Transmembrane Transport Hormone Secretion Hormone Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Regulation Of Blood Pressure Signal Release Regulation Of Heart Contraction Transmembrane Signaling Receptor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Blood Circulation Learning Or Memory Signaling Receptor Activity Cognition Positive Regulation Of Catalytic Activity Response To Peptide Hormone
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