UGT1A10

Name	UDP glucuronosyltransferase family 1 member A10
Structure	No pdb structure
Interactors	1 interactors: APP
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Retinoic Acid Binding Enzyme Inhibitor Activity Protein Kinase C Binding Protein Binding UDP-glycosyltransferase Activity Glucuronosyltransferase Activity Transferase Activity Glycosyltransferase Activity Enzyme Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Liver Development Lipid Metabolic Process Xenobiotic Metabolic Process Toxin Catabolic Process Xenobiotic Catabolic Process Negative Regulation Of Fatty Acid Metabolic Process Flavone Metabolic Process
Pathways	Glucuronidation Paracetamol ADME
GWAS	Bilirubin levels ( 32084209 ) Cholelithiasis-related traits in sickle cell anemia ( 22558097 ) Hair greying ( 26926045 ) Late-onset Alzheimer's disease ( 27770636 ) Liver disease biomarker ( 30576415 ) Low density lipoprotein cholesterol levels ( 32154731 ) N-desmethylclozapine concentration in schizophrenia ( 32555152 ) Neuroblastoma or malignant cutaneous melanoma ( 31605138 ) Serum metabolite concentrations in chronic kidney disease ( 33838163 ) Serum metabolite levels ( 23093944 33031748 ) Total bilirubin levels ( 29403010 ) Total bilirubin levels in HIV-1 infection ( 25884002 )
Entrez ID	54575
HPRD ID	07336
Ensembl ID	ENSG00000242515
Uniprot IDs	Q5DT02 Q9HAW8
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding