MTMR12

Description		myotubularin related protein 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Sarcoplasmic Reticulum Sarcomere
	Molecular Function	Protein Binding
	Biological Process
Pathways		Synthesis of PIPs at the early endosome membrane
Drugs
Diseases
GWAS		Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)
Interacting Genes		1 interacting genes: MTM1
Entrez ID		54545
HPRD ID		05933
Ensembl ID		ENSG00000150712
Uniprot IDs		Q9C0I1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Striated Muscle Tissue Development Phosphatidylinositol-3-phosphate Phosphatase Activity Muscle Cell Cellular Homeostasis Negative Regulation Of Autophagosome Assembly Intermediate Filament Binding Positive Regulation Of Skeletal Muscle Tissue Growth Phosphatidylinositol Dephosphorylation Skeletal Muscle Tissue Growth I Band Regulation Of Skeletal Muscle Tissue Development Regulation Of Skeletal Muscle Tissue Growth Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Mitochondrion Distribution Positive Regulation Of Skeletal Muscle Tissue Development Phospholipid Dephosphorylation Regulation Of Autophagosome Assembly Regulation Of Striated Muscle Tissue Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Muscle Organ Development Negative Regulation Of Macroautophagy Sarcomere Endosome To Lysosome Transport Mitochondrion Localization Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Vacuole Organization Intermediate Filament Organization Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Filopodium Protein Dephosphorylation Autophagosome Assembly Negative Regulation Of TOR Signaling TOR Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Negative Regulation Of Autophagy Autophagosome Organization Ruffle Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Binding Lysosomal Transport Negative Regulation Of Protein Catabolic Process Phosphatidylinositol Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Dephosphorylation Phosphoprotein Phosphatase Activity Lipid Modification Negative Regulation Of Proteolysis
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