HAO1

Gene Name		hydroxyacid oxidase (glycolate oxidase) 1
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Gene Ontology Annotations	Cellular Component	Peroxisome Peroxisomal Matrix
	Molecular Function	(S)-2-hydroxy-acid Oxidase Activity Receptor Binding Glycolate Oxidase Activity FMN Binding Glyoxylate Oxidase Activity Very-long-chain-(S)-2-hydroxy-acid Oxidase Activity Long-chain-(S)-2-hydroxy-long-chain-acid Oxidase Activity Medium-chain-(S)-2-hydroxy-acid Oxidase Activity
	Biological Process	Fatty Acid Alpha-oxidation Response To Oxidative Stress Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Glycolate Catabolic Process Glyoxylate Metabolic Process
Pathways		Glyoxylate metabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Colorectal cancer ( 23263487)
Protein-protein Interactions		1 interactors: PEX5
Entrez ID		54363
HPRD ID		05429
Ensembl ID		ENSG00000101323
Uniprot IDs		A8K058 Q9UJM8
PDB IDs		2NZL 2RDT 2RDU 2RDW 2W0U
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Negative Regulation Of Protein Oligomerization Protein Import Into Peroxisome Matrix Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Very Long-chain Fatty Acid Metabolic Process Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Endoplasmic Reticulum Organization Fatty Acid Beta-oxidation Peroxisome Organization Positive Regulation Of Multicellular Organism Growth Intracellular Protein Transmembrane Transport Mitochondrial Membrane Organization Protein Transmembrane Transport Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cerebral Cortex Cell Migration Membrane Docking Regulation Of Multicellular Organism Growth Telencephalon Cell Migration Forebrain Cell Migration Protein Tetramerization Neuromuscular Process Negative Regulation Of Protein Complex Assembly Cellular Lipid Catabolic Process Positive Regulation Of Developmental Growth Cerebral Cortex Development Protein Import Protein Targeting To Membrane Neuron Migration Lipid Modification Carboxylic Acid Catabolic Process Pallium Development Central Nervous System Neuron Differentiation Positive Regulation Of Growth Establishment Of Protein Localization To Membrane Lipid Catabolic Process Telencephalon Development Regulation Of Developmental Growth Fatty Acid Metabolic Process Regulation Of Protein Complex Assembly Establishment Of Protein Localization To Organelle
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