A4GALT

Description		alpha 1,4-galactosyltransferase (P1PK blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Galactosyltransferase Activity Toxic Substance Binding Transferase Activity Glycosyltransferase Activity Hexosyltransferase Activity Lactosylceramide 4-alpha-galactosyltransferase Activity
	Biological Process	Globoside Biosynthetic Process Lipid Metabolic Process Glycosphingolipid Biosynthetic Process Plasma Membrane Organization
Pathways		Glycosphingolipid biosynthesis
Drugs
Diseases
GWAS		Asthma ( 27611488) Blood protein levels ( 30072576) Estimated glomerular filtration rate ( 31451708 31152163) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glycated hemoglobin levels ( 34059833) HDL cholesterol levels ( 32203549) Hematocrit ( 27863252 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Mean corpuscular volume ( 29403010) Mean platelet volume ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 31628463) Platelet distribution width ( 27863252) Plateletcrit ( 32888494) Red blood cell count ( 27863252 32888494) Resting metabolic rate ( 28476931) Serum metabolite levels ( 33031748)
Interacting Genes		1 interacting genes: CFTR
Entrez ID		53947
HPRD ID		06390
Ensembl ID		ENSG00000128274
Uniprot IDs		A0A0S2Z5J1 Q5D079 Q9NPC4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cellular PH Regulation Of Transmembrane Transporter Activity Membrane Docking Positive Regulation Of Exocytosis
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