CSNK1G1

Description		casein kinase 1 gamma 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Endocytosis Signal Transduction Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs		2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol
Diseases
GWAS		Basophil count ( 32888494) General factor of neuroticism ( 30867560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monoclonal gammopathy of undetermined significance ( 30737484) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Myeloid white cell count ( 27863252) Neuroticism ( 29255261) White blood cell count ( 32888494)
Interacting Genes		13 interacting genes: APP CEP76 CLSPN FAM219A FOXO1 IKZF1 KRTAP10-7 MKRN1 PPP1R14A RELA RUNDC3B SNCA WDCP
Entrez ID		53944
HPRD ID		05886
Ensembl ID		ENSG00000169118
Uniprot IDs		Q8IXA3 Q9HCP0 U3KQB3
PDB IDs		2CMW
Enriched GO Terms of Interacting Partners?		Response To Interleukin-1 Negative Regulation Of MiRNA Transcription Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Presynapse Assembly Regulation Of Protein Catabolic Process Amyloid Fibril Formation Positive Regulation Of Small Molecule Metabolic Process Protein-containing Complex Regulation Of Neurotransmitter Uptake Positive Regulation Of Amyloid Precursor Protein Catabolic Process Cellular Response To Copper Ion Microglial Cell Activation Response To Copper Ion Leukocyte Activation Involved In Inflammatory Response Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Oxidative Stress Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Complex Oligomerization Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Interleukin-1 Beta Production Cellular Response To Chemical Stress Macrophage Activation Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Cellular Response To Growth Factor Stimulus Positive Regulation Of Reactive Oxygen Species Metabolic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Positive Regulation Of Phosphate Metabolic Process Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Negative Regulation Of RNA Biosynthetic Process Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Endothelin Production
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