DUOX1

Description		dual oxidase 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Cell Leading Edge NADPH Oxidase Complex
	Molecular Function	Peroxidase Activity Calcium Ion Binding Protein Binding NAD(P)H Oxidase H2O2-forming Activity Superoxide-generating NAD(P)H Oxidase Activity Oxidoreductase Activity Heme Binding Metal Ion Binding NADP Binding
	Biological Process	Thyroid Hormone Generation Defense Response Response To Oxidative Stress Cytokine-mediated Signaling Pathway Cuticle Development Hormone Biosynthetic Process Superoxide Anion Generation Hydrogen Peroxide Catabolic Process Hydrogen Peroxide Biosynthetic Process Response To CAMP Cellular Response To Cytokine Stimulus Reactive Oxygen Species Metabolic Process Positive Regulation Of Wound Healing Cellular Oxidant Detoxification Positive Regulation Of Cell Motility
Pathways		Thyroxine biosynthesis
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: TPO TXNDC11
Entrez ID		53905
HPRD ID		08421
Ensembl ID		ENSG00000137857
Uniprot IDs		Q9NRD9
PDB IDs		7D3E 7D3F
Enriched GO Terms of Interacting Partners?		Iodide Peroxidase Activity Thyroid Hormone Generation Embryonic Hemopoiesis Thyroid Hormone Metabolic Process Hydrogen Peroxide Catabolic Process Peroxidase Activity Hydrogen Peroxide Metabolic Process Hormone Biosynthetic Process Phenol-containing Compound Metabolic Process Cellular Oxidant Detoxification Reactive Oxygen Species Metabolic Process Cellular Detoxification Heme Binding
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