TRIM34

Description		tripartite motif containing 34
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response Defense Response To Virus Regulation Of Primary Metabolic Process
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Malaria ( 31844061) Mean corpuscular hemoglobin concentration ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		10 interacting genes: BIRC2 MKRN3 MNAT1 TRIM5 UBE2D2 UBE2K UBE2N UBE2U USP2 ZBP1
Entrez ID		53840
HPRD ID		16141
Ensembl ID		ENSG00000258659
Uniprot IDs		Q9BYJ4
PDB IDs		2EGP
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Post-translational Protein Modification Ubiquitin Conjugating Enzyme Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-protein Transferase Activity Protein Modification Process Positive Regulation Of Protein K63-linked Ubiquitination Modification-dependent Protein Catabolic Process Transferase Activity Ubiquitin-dependent Protein Catabolic Process Proteolysis Proteolysis Involved In Protein Catabolic Process Protein Metabolic Process Regulation Of Protein K63-linked Ubiquitination Ubiquitin Protein Ligase Activity Positive Regulation Of Protein Polyubiquitination Positive Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Innate Immune Response Macromolecule Metabolic Process Regulation Of Immune Response Regulation Of Protein Polyubiquitination Regulation Of Necroptotic Process Macromolecule Catabolic Process Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Canonical NF-kappaB Signal Transduction Catabolic Process Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Immune Response Defense Response To Virus Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Innate Immune Response Ubiquitin Protein Ligase Binding Left-handed Z-DNA Binding Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Response To Cytokine Stimulus Protein K63-linked Ubiquitination Regulation Of Defense Response Nucleus Antiviral Innate Immune Response Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Protein Modification Process Regulation Of Immune System Process FBXO Family Protein Binding Omegasome Positive Regulation Of Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Response To Virus Ubiquitin Binding
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