PNOC

Gene Name		prepronociceptin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region
	Molecular Function	Opioid Peptide Activity Neuropeptide Hormone Activity Protein Binding
	Biological Process	Signal Transduction Neuropeptide Signaling Pathway Synaptic Transmission Sensory Perception
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: OPRL1
Entrez ID		5368
HPRD ID		03268
Ensembl ID		ENSG00000168081
Uniprot IDs		Q13519
PDB IDs
Enriched GO Terms of Interacting Partners?		Opioid Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Sensory Perception Of Pain Neuropeptide Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Ion Homeostasis Synaptic Transmission Behavior
Tagcloud ?		1beta antagonized cultures curve cytokine cytokines extents feedback fq incubation inf lipopolysaccharide lps mediators modulation nociceptin nop normalized orphanin prepro quartile rd respective st supernatants suppress varying volunteers whole