TPCN1

Description		two pore segment channel 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Endosome Membrane Membrane Early Endosome Membrane Monoatomic Ion Channel Complex Endolysosome Recycling Endosome Membrane
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Sodium Channel Activity Calcium Channel Activity Protein Binding Ligand-gated Sodium Channel Activity Syntaxin Binding Voltage-gated Channel Activity Identical Protein Binding Protein Homodimerization Activity NAADP-sensitive Calcium-release Channel Activity Phosphatidylinositol-3,5-bisphosphate Binding Intracellularly Phosphatidylinositol-3,5-bisphosphate-gated Monatomic Cation Channel Activity
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Positive Regulation Of Autophagy Calcium-mediated Signaling Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport Endocytosis Involved In Viral Entry Into Host Cell
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS		Response to fenofibrate (adiponectin levels) ( 23149075)
Novel Interacting Genes		1 novel interacting genes: IFT81
Interacting Genes
Entrez ID		53373
HPRD ID		18217
Ensembl ID		ENSG00000186815
Uniprot IDs		B3KSG7 B7Z3R2 Q9ULQ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Intraciliary Transport Particle B Intraciliary Anterograde Transport Sperm Flagellum Assembly Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Motile Cilium Assembly Sperm Principal Piece Sperm Midpiece Ciliary Tip Tubulin Binding Regulation Of Smoothened Signaling Pathway Microtubule Organizing Center Centriole Transport Along Microtubule Microtubule-based Transport Motile Cilium Cytoskeleton-dependent Intracellular Transport
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