ATP6V1C1

Description		ATPase H+ transporting V1 subunit C1
Image
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Membrane Proton-transporting Two-sector ATPase Complex Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Apical Part Of Cell Synapse Extracellular Exosome Extrinsic Component Of Synaptic Vesicle Membrane ATPase Complex
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Monoatomic Ion Transport Regulation Of Macroautophagy Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs		Tiludronic acid D-tartaric acid Thonzonium
Diseases
GWAS		Antisaccade task score ( 31596458) Small vessel stroke ( 29123153) Spatial processing ( 31596458)
Novel Interacting Genes		1 novel interacting genes: PABPC1
Interacting Genes
Entrez ID		528
HPRD ID		04371
Ensembl ID		ENSG00000155097
Uniprot IDs		A0A024R9I0 P21283
PDB IDs		6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Translation Activator Activity MCRD-mediated MRNA Stability Complex Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay CRD-mediated MRNA Stabilization Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Poly(U) RNA Binding Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic Translation Poly(A) Binding Positive Regulation Of Viral Genome Replication Regulation Of Cytoplasmic Translation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cell Leading Edge Positive Regulation Of Viral Process MRNA Stabilization Negative Regulation Of MRNA Catabolic Process Regulation Of Viral Genome Replication RNA Stabilization Cytoplasmic Ribonucleoprotein Granule Catalytic Step 2 Spliceosome Negative Regulation Of RNA Catabolic Process Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Viral Life Cycle MRNA 3'-UTR Binding MRNA Catabolic Process Regulation Of Viral Process Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Translation Regulatory NcRNA-mediated Gene Silencing Spliceosomal Complex RNA Catabolic Process Regulation Of MRNA Stability RNA Splicing, Via Transesterification Reactions Regulation Of RNA Stability MRNA Splicing, Via Spliceosome Lamellipodium MRNA Binding Regulation Of MRNA Metabolic Process Nucleobase-containing Compound Catabolic Process RNA Splicing Negative Regulation Of Catabolic Process Ribonucleoprotein Complex
Tagcloud ?