SERPINB10

Description		serpin family B member 10
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity
	Biological Process
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Asthma ( 31619474) Cognitive performance (processing speed) ( 31598132) Cutaneous leishmaniasis ( 32830257) Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: CFTR SRPK1
Entrez ID		5273
HPRD ID		03635
Ensembl ID		ENSG00000242550
Uniprot IDs		B2RC45 P48595
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Sperm DNA Condensation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Positive Regulation Of Viral Genome Replication Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication ATP Binding Cellular Response To CAMP Nucleotide Binding Endoplasmic Reticulum Regulation Of Cellular PH Regulation Of Transmembrane Transporter Activity Cholesterol Transport Membrane Docking
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