PHKG2

Name	phosphorylase kinase catalytic subunit gamma 2
Structure
Interactors	4 interactors: DAPK1 MAGEA2 MAGEA2B PHKG1
GO Annotations	Cellular Component	Cytoplasm Cytosol Phosphorylase Kinase Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Phosphorylase Kinase Activity Protein Binding Calmodulin Binding ATP Binding Kinase Activity Transferase Activity Enzyme Binding Tau-protein Kinase Activity
	Biological Process	Glycogen Metabolic Process Glycogen Catabolic Process Generation Of Precursor Metabolites And Energy Protein Phosphorylation Signal Transduction Positive Regulation Of Glycogen Catabolic Process
Pathways	Glycogen breakdown (glycogenolysis)
Diseases	Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS	No GWAS studies recorded
Entrez ID	5261
HPRD ID	01405
Ensembl ID	ENSG00000156873
Uniprot IDs	P15735
PDB IDs	2Y7J
GO Terms Enriched among Interactors ?	Negative Regulation Of Protein Acetylation Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Sumoylation Regulation Of Ubiquitin-protein Transferase Activity Cellular Senescence DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Negative Regulation Of Protein Metabolic Process Signal Transduction By P53 Class Mediator Negative Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Ubiquitination PML Body Positive Regulation Of Post-translational Protein Modification Histone Deacetylase Binding DNA-binding Transcription Factor Binding Calmodulin Binding Regulation Of Protein Ubiquitination Regulation Of NMDA Receptor Activity Phosphorylase Kinase Activity Regulation Of Post-translational Protein Modification Phosphorylase Kinase Complex Ubiquitin Protein Ligase Binding Positive Regulation Of Catalytic Activity Cellular Response To Hydroperoxide Defense Response To Tumor Cell Protein Serine Kinase Activity Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Protein Serine/threonine Kinase Activity Signal Transduction Regulation Of Neurotransmitter Receptor Activity Intracellular Signal Transduction Syntaxin-1 Binding Response To Hydroperoxide Protein Kinase Activity Calcium/calmodulin-dependent Protein Kinase Activity Regulation Of Catalytic Activity Macromolecule Metabolic Process Regulation Of Response To Tumor Cell Kinase Activity Protein Catabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Signaling Receptor Activity Regulation Of Protein Modification Process Organelle Negative Regulation Of Biosynthetic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Metabolic Process